BCMA CHIMERIC ANTIGEN RECEPTOR BASED ON SINGLE DOMAIN ANTIBODY AND USE THEREOF

A chimeric antigen receptor (CAR) and the use thereof, the CAR comprising: a BCMA binding domain, a transmembrane domain, one or more co-stimulatory domains, and an intracellular signaling domain, wherein the BCMA binding domain comprises heavy chain complementarity determining regions HCDR1-3, and...

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Bibliographische Detailangaben
Hauptverfasser: BAO, CHAOLEMENG, SU, HONGCHANG, ZHANG, JISHUAI, CAI, QINGHUA, CAI, ZHIBO, LI, HONGJIAN, SONG, ZONGPEI, DING, YIJIN
Format: Patent
Sprache:eng ; fre
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