CRYSTALLINE FORMS OF N1-(1-CYANOCYCLOPROPLY)-N2-((1S)-1-{4'-[(1R-2,2-DIFLUORO-1-HYDROXYETHYL]BIPHENYL-4-YL}-2,2,2-TRIFLUOROETHYL)-4-FLUORO-L-LEUCINAMIDE

CRYSTALLINE FORMS OF N1-(1-CYANOCYCLOPROPLY)-N2-((1S)-1-{4'-[(1R-2,2-DIFLUORO-1-HYDROXYETHYL]BIPHENYL-4-YL}-2,2,2-TRIFLUOROETHYL)-4-FLUORO-L-LEUCINAMIDE

The present disclosure encompasses crystalline forms of N1-(1-cyanocycloproply)-N2- ((1S)-1-{4'-[(1R-2,2-difluoro-1-hydroxyethyl]biphenyl-4-yl}-2,2,2-trifluoroethyl)-4-fluoro-L- leucinamide and processes for the preparation thereof. La présente invention concerne des formes cristallines de N1-(...

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Hauptverfasser: SCHOELL, JOCHEN, NIEDERMANN, HANS PETER, VEIT, STEPHAN, STUEBER, DIRK, PETROVA, ROSITZA IORDANOVA, BAZIN, CYNTHIA, CHASSAING, CHRISTOPHE PIERRE ALAIN, JIN, XIAOLING, SCHEIPERS, CLAUDIA
Format: Patent
Sprache:eng ; fre
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:The present disclosure encompasses crystalline forms of N1-(1-cyanocycloproply)-N2- ((1S)-1-{4'-[(1R-2,2-difluoro-1-hydroxyethyl]biphenyl-4-yl}-2,2,2-trifluoroethyl)-4-fluoro-L- leucinamide and processes for the preparation thereof. La présente invention concerne des formes cristallines de N1-(1-cyanocycloproply)-N2- ((1S)-1-{4'-[(1R-2,2-difluoro-1-hydroxyéthyl]biphényl-4-yl}-2,2,2-trifluoroéthyl)-4-fluoro-L- leucinamide et leurs procédés de préparation.