OLIGONUCLEOTIDES COMPRISING A PHOSPHOROTRITHIOATE INTERNUCLEOSIDE LINKAGE

The present invention relates to an oligonucleotide comprising at least one phosphorotrithioate internucleoside linkage of formula (I) as defined in the description and in the claim. The oligonucleotide of the invention can be used as a medicament. La présente invention concerne un oligonucléotide c...

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Bibliographische Detailangaben
Hauptverfasser:	KOCH, TROELS, DUSCHMALE, JOERG JAKOB ANDREAS, DUSCHMALE, MARTINA BRIGITTE, BLEICHER, KONRAD, LI, MEILING, KOLLER, ERICH, SCHAEUBLIN, ADRIAN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	The present invention relates to an oligonucleotide comprising at least one phosphorotrithioate internucleoside linkage of formula (I) as defined in the description and in the claim. The oligonucleotide of the invention can be used as a medicament. La présente invention concerne un oligonucléotide comprenant au moins une liaison internucléosidique phosphorodithioate de formule (I) tel que défini dans la description et les revendications. L'oligonucléotide selon l'invention peut être utilisé en tant que médicament.