PHARMACEUTICAL 6,5 HETEROBICYCLIC RING DERIVATIVES

The invention relates to 6,5 heterobicyclic ring derivatives of formula (I), processes for preparing them, pharmaceutical compositions containing them and their use for the treatment of inflammatory conditions driven by STING activation, such as, but not confined to, SLE and geographic atrophy. L�...

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Hauptverfasser: HALLSIDE, MICHAL SARAH, RICHARDSON, ANTHONY JOHN, LOWE, MARTIN ALEXANDER, HEER, JAG PAUL, LALLEMAND, BENEDICTE, TOWNSEND, ROBERT JAMES, SMALLEY, ADAM PETER, LLAVERIA CROS, JOSEP, LI, XIANFU
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The invention relates to 6,5 heterobicyclic ring derivatives of formula (I), processes for preparing them, pharmaceutical compositions containing them and their use for the treatment of inflammatory conditions driven by STING activation, such as, but not confined to, SLE and geographic atrophy. L'invention concerne des dérivés cycliques 6,5 hétérobicycliques de formule (I), leurs procédés de préparation, des compositions pharmaceutiques les contenant et leur utilisation pour le traitement d'états inflammatoires entraînés par activation STING, tels que, mais pas confinés à, SLE et l'atrophie géographique.