TETRAHYDROQUINAZOLINE DERIVATIVES USEFUL AS ANTICANCER AGENTS

Compounds of the general formula (l): are provided, together with processes for the preparation of these compounds, compositions containing these compounds, and the uses of these compounds as KRAS inihibitors, which may be used in the treatment of cancer. L'invention concerne des composés de fo...

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Hauptverfasser: MADERNA, ANDREAS, PALMER, CYNTHIA, BROOUN, ALEXEI, CHEN, PING, COLLINS, MICHAEL RAYMOND, LINTON, MARIA ANGELICA, SPANGLER, JILLIAN ELYSE, CHENG, HENGMIAO, NAGATA, ASAKO, PLANKEN, SIMON
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Compounds of the general formula (l): are provided, together with processes for the preparation of these compounds, compositions containing these compounds, and the uses of these compounds as KRAS inihibitors, which may be used in the treatment of cancer. L'invention concerne des composés de formule générale (I), des procédés pour la préparation de ces composés, des compositions contenant ces composés, et les utilisations de ces composés.