MODIFIED IMMUNOMODULATORY PEPTIDE

Modified polypeptides derived from the pyrin-domain of IFI16 are provided as well as their uses in medicine. Specifically, the polypeptides are provided for use in the treatment of disorders associated with STING activity, including cancer and immunodeficient or auto-immune disorders. L'inventi...

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Bibliographische Detailangaben
Hauptverfasser:	JAKOBSEN ROELSGAARD, MARTIN, OLESEN ELSBORG, CLAUS
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Modified polypeptides derived from the pyrin-domain of IFI16 are provided as well as their uses in medicine. Specifically, the polypeptides are provided for use in the treatment of disorders associated with STING activity, including cancer and immunodeficient or auto-immune disorders. L'invention concerne des polypeptides modifiés dérivés du domaine pyrine de l'IFI16 ainsi que leurs utilisations en médecine. Plus particulièrement, l'invention concerne des polypeptides destinés à être utilisés dans le traitement de troubles associés à l'activité STING, y compris le cancer et des troubles immuno-déficients ou auto-immuns.