DOSAGE REGIMEN OF VIDOFLUDIMUS FOR USE IN THE PREVENTION OR TREATMENT OF CHRONIC INFLAMMATORY AND/OR AUTOIMMUNE DISEASES

The present invention refers to a 2-({3-fluoro-3'-methoxy-[1,1'-biphenyl]-4- yl}carbamoyl)cyclopent-1-ene-1-carboxylic acid) according to formula (I) and a novel dosage regimen as well as their uses in the treatment of chronic inflammatory and/or autoimmune diseases. The said compound of f...

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Bibliographische Detailangaben
Hauptverfasser: KOHLHOF, HELLA, VITT, DANIEL, GROPPEL, MANFRED, MUHLER, ANDREAS
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention refers to a 2-({3-fluoro-3'-methoxy-[1,1'-biphenyl]-4- yl}carbamoyl)cyclopent-1-ene-1-carboxylic acid) according to formula (I) and a novel dosage regimen as well as their uses in the treatment of chronic inflammatory and/or autoimmune diseases. The said compound of formula (I) inhibits dihydroorotate dehydrogenase (DHODH), and is known for the treatment and prevention of diseases, in particular their use in diseases where there is an advantage in inhibiting dihydroorotate dehydrogenase (DHODH). La présente invention concerne un 2-({3-fluoro-3'-methoxy-[1,1'-biphényl]-4- yl}carbamoyl)cyclopent-1-ène-1-acide carboxylique) selon la formule (I) et une nouvelle posologie, ainsi que leurs utilisations dans le traitement de maladies inflammatoires chroniques et/ou auto-immunes. Ledit composé de formule (I) inhibe la dihydroorotate déshydrogénase (DHODH), et est connu pour le traitement et la prévention de maladies, en particulier son utilisation dans des maladies où il est bénéfique d'inhiber la dihydroorotate déshydrogénase (DHODH).