BIOMARKERS OF PRETERM BIRTH

The present invention relates to biomarkers, and particularly, although not exclusively, to biomarkers of preterm birth. The biomarkers are useful, several weeks or months prior to birth, for distinguishing individuals at risk of experiencing birth before 37 weeks of gestation. The biomarkers, namel...

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Bibliographische Detailangaben
Hauptverfasser:	ARBEL, NIR, LEOW, SAN MIN, RUBIN, EITAN, LIN, XIANG QIAN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to biomarkers, and particularly, although not exclusively, to biomarkers of preterm birth. The biomarkers are useful, several weeks or months prior to birth, for distinguishing individuals at risk of experiencing birth before 37 weeks of gestation. The biomarkers, namely ECM1, FGA, EFEMP1 GGH, PEDF, PTN and LAMC2, are identified by a proteomics analysis, as being differentially expressed in vaginal fluid by women going to have preterm birth. La présente invention concerne des biomarqueurs, et notamment, mais non exclusivement, des biomarqueurs de naissance prématurée. Les biomarqueurs sont utiles, plusieurs semaines ou mois avant la naissance, pour distinguer des individus à risque d'accoucher avant 37 semaines de gestation. Les biomarqueurs, à savoir ECM1, FGA, EFEMP1, GGH, PEDF, PTN et LAMC2, sont identifiés par une analyse protéomique, comme étant différentiellement exprimés dans les sécrétions vaginales par des femmes qui va avoir un accouchement prématuré.