USE OF SYNCYTIN FOR TARGETING DRUG AND GENE DELIVERY TO LUNG TISSUE

The invention relates to a pharmaceutical composition for targeting drug delivery including gene delivery to lung tissue, comprising at least a therapeutic drug or gene associated to a syncytin protein, and its use in the prevention and/or treatment of lung diseases, in particular in gene therapy of...

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Bibliographische Detailangaben
Hauptverfasser:	GALY, ANNE, FERRAND, MAXIME, COQUIN, YOUNA
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to a pharmaceutical composition for targeting drug delivery including gene delivery to lung tissue, comprising at least a therapeutic drug or gene associated to a syncytin protein, and its use in the prevention and/or treatment of lung diseases, in particular in gene therapy of said diseases using lentiviral vector particles or lentivirus-like particles pseudotyped with syncytin protein. L'invention concerne une composition pharmaceutique pour le ciblage d'administration de médicament comprenant l'administration de gène au tissu pulmonaire, comprenant au moins un médicament ou un gène thérapeutique associé à une protéine syncytine, et son utilisation dans la prévention et/ou le traitement de maladies pulmonaires, en particulier dans la thérapie génique desdites maladies à l'aide de particules de vecteur lentiviral ou de particules de type lentivirus pseudotypées avec la protéine syncytine.