USE OF SYNCYTIN FOR TARGETING DRUG AND GENE DELIVERY TO REGENERATING MUSCLE TISSUE

The invention relates to a pharmaceutical composition for targeting drug delivery including gene delivery to regenerating muscle tissue, comprising at least a therapeutic drug or gene, associated to a syncytin protein, and its use in the prevention and/or treatment of muscle injuries or diseases, in...

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Hauptverfasser: GALY, ANNE, FERRAND, MAXIME
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creator GALY, ANNE
FERRAND, MAXIME
description The invention relates to a pharmaceutical composition for targeting drug delivery including gene delivery to regenerating muscle tissue, comprising at least a therapeutic drug or gene, associated to a syncytin protein, and its use in the prevention and/or treatment of muscle injuries or diseases, in particular in gene therapy of said diseases using lentiviral vector particles or lentivirus-like particles pseudotyped with syncytin protein. L'invention concerne une composition pharmaceutique permettant le ciblage de l'administration de médicaments, y compris l'administration de gènes, en vue de régénérer un tissu musculaire, comprenant au moins un médicament ou gène thérapeutiques, associés à une protéine de syncytine, ainsi que son utilisation dans la prévention et/ou le traitement de lésions ou de maladies musculaires, en particulier dans la thérapie génique desdites maladies à l'aide de particules de vecteurs lentiviraux ou de particules de type lentivirus pseudotypées avec la protéine de syncytine.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title USE OF SYNCYTIN FOR TARGETING DRUG AND GENE DELIVERY TO REGENERATING MUSCLE TISSUE
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