BRD4 INHIBITOR
The present invention provides a BRD inhibitor as shown in formula II, belonging to the field of compound drugs. BRD4 inhibitors have great value as anti-cancer and anti-inflammatory compounds. The compound according to the invention has a good inhibitory effect on prostate cancer cell proliferation...
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| creator | CHEN, YUANWEI LI, XINGHAI FAN, LEI XU, KEXIN WANG, FEI LUO, TONGCHUAN ZHANG, SHAOHUA WU, XIAOQUAN CHEN, KE |
| description | The present invention provides a BRD inhibitor as shown in formula II, belonging to the field of compound drugs. BRD4 inhibitors have great value as anti-cancer and anti-inflammatory compounds. The compound according to the invention has a good inhibitory effect on prostate cancer cell proliferation, and can be used for preparing a drug combatting tumours, autoimmune or inflammatory diseases and viral infection, and in particular an anti-prostate cancer drug.
Il est décrit un inhibiteur du bromodomaine figurant dans la formule II, lequel a trait au domaine des médicaments composés. Les inhibiteurs du bromodomaine 4 ont une grande valeur comme composés anti-cancéreux et anti-inflammatoires. Le composé selon l'invention a un bon effet inhibiteur sur la prolifération de cellules de cancer de la prostate, et il peut être utilisé pour la préparation d'un médicament combattant les tumeurs, les maladies auto-immunes ou inflammatoires et les infections virales, ainsi que pour la préparation d'un médicament combattant le cancer de la prostate. |
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Il est décrit un inhibiteur du bromodomaine figurant dans la formule II, lequel a trait au domaine des médicaments composés. Les inhibiteurs du bromodomaine 4 ont une grande valeur comme composés anti-cancéreux et anti-inflammatoires. Le composé selon l'invention a un bon effet inhibiteur sur la prolifération de cellules de cancer de la prostate, et il peut être utilisé pour la préparation d'un médicament combattant les tumeurs, les maladies auto-immunes ou inflammatoires et les infections virales, ainsi que pour la préparation d'un médicament combattant le cancer de la prostate.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230919&DB=EPODOC&CC=CA&NR=3075435C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230919&DB=EPODOC&CC=CA&NR=3075435C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CHEN, YUANWEI</creatorcontrib><creatorcontrib>LI, XINGHAI</creatorcontrib><creatorcontrib>FAN, LEI</creatorcontrib><creatorcontrib>XU, KEXIN</creatorcontrib><creatorcontrib>WANG, FEI</creatorcontrib><creatorcontrib>LUO, TONGCHUAN</creatorcontrib><creatorcontrib>ZHANG, SHAOHUA</creatorcontrib><creatorcontrib>WU, XIAOQUAN</creatorcontrib><creatorcontrib>CHEN, KE</creatorcontrib><title>BRD4 INHIBITOR</title><description>The present invention provides a BRD inhibitor as shown in formula II, belonging to the field of compound drugs. BRD4 inhibitors have great value as anti-cancer and anti-inflammatory compounds. The compound according to the invention has a good inhibitory effect on prostate cancer cell proliferation, and can be used for preparing a drug combatting tumours, autoimmune or inflammatory diseases and viral infection, and in particular an anti-prostate cancer drug.
Il est décrit un inhibiteur du bromodomaine figurant dans la formule II, lequel a trait au domaine des médicaments composés. Les inhibiteurs du bromodomaine 4 ont une grande valeur comme composés anti-cancéreux et anti-inflammatoires. Le composé selon l'invention a un bon effet inhibiteur sur la prolifération de cellules de cancer de la prostate, et il peut être utilisé pour la préparation d'un médicament combattant les tumeurs, les maladies auto-immunes ou inflammatoires et les infections virales, ainsi que pour la préparation d'un médicament combattant le cancer de la prostate.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZOBzCnIxUfD08_B08gzxD-JhYE1LzClO5YXS3Azybq4hzh66qQX58anFBYnJqXmpJfHOjsYG5qYmxqbOxoRVAABK2hvl</recordid><startdate>20230919</startdate><enddate>20230919</enddate><creator>CHEN, YUANWEI</creator><creator>LI, XINGHAI</creator><creator>FAN, LEI</creator><creator>XU, KEXIN</creator><creator>WANG, FEI</creator><creator>LUO, TONGCHUAN</creator><creator>ZHANG, SHAOHUA</creator><creator>WU, XIAOQUAN</creator><creator>CHEN, KE</creator><scope>EVB</scope></search><sort><creationdate>20230919</creationdate><title>BRD4 INHIBITOR</title><author>CHEN, YUANWEI ; LI, XINGHAI ; FAN, LEI ; XU, KEXIN ; WANG, FEI ; LUO, TONGCHUAN ; ZHANG, SHAOHUA ; WU, XIAOQUAN ; CHEN, KE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA3075435C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2023</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>CHEN, YUANWEI</creatorcontrib><creatorcontrib>LI, XINGHAI</creatorcontrib><creatorcontrib>FAN, LEI</creatorcontrib><creatorcontrib>XU, KEXIN</creatorcontrib><creatorcontrib>WANG, FEI</creatorcontrib><creatorcontrib>LUO, TONGCHUAN</creatorcontrib><creatorcontrib>ZHANG, SHAOHUA</creatorcontrib><creatorcontrib>WU, XIAOQUAN</creatorcontrib><creatorcontrib>CHEN, KE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CHEN, YUANWEI</au><au>LI, XINGHAI</au><au>FAN, LEI</au><au>XU, KEXIN</au><au>WANG, FEI</au><au>LUO, TONGCHUAN</au><au>ZHANG, SHAOHUA</au><au>WU, XIAOQUAN</au><au>CHEN, KE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>BRD4 INHIBITOR</title><date>2023-09-19</date><risdate>2023</risdate><abstract>The present invention provides a BRD inhibitor as shown in formula II, belonging to the field of compound drugs. BRD4 inhibitors have great value as anti-cancer and anti-inflammatory compounds. The compound according to the invention has a good inhibitory effect on prostate cancer cell proliferation, and can be used for preparing a drug combatting tumours, autoimmune or inflammatory diseases and viral infection, and in particular an anti-prostate cancer drug.
Il est décrit un inhibiteur du bromodomaine figurant dans la formule II, lequel a trait au domaine des médicaments composés. Les inhibiteurs du bromodomaine 4 ont une grande valeur comme composés anti-cancéreux et anti-inflammatoires. Le composé selon l'invention a un bon effet inhibiteur sur la prolifération de cellules de cancer de la prostate, et il peut être utilisé pour la préparation d'un médicament combattant les tumeurs, les maladies auto-immunes ou inflammatoires et les infections virales, ainsi que pour la préparation d'un médicament combattant le cancer de la prostate.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | BRD4 INHIBITOR |
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