BRD4 INHIBITOR

The present invention provides a BRD inhibitor as shown in formula II, belonging to the field of compound drugs. BRD4 inhibitors have great value as anti-cancer and anti-inflammatory compounds. The compound according to the invention has a good inhibitory effect on prostate cancer cell proliferation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	CHEN, YUANWEI, LI, XINGHAI, FAN, LEI, XU, KEXIN, WANG, FEI, LUO, TONGCHUAN, ZHANG, SHAOHUA, WU, XIAOQUAN, CHEN, KE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides a BRD inhibitor as shown in formula II, belonging to the field of compound drugs. BRD4 inhibitors have great value as anti-cancer and anti-inflammatory compounds. The compound according to the invention has a good inhibitory effect on prostate cancer cell proliferation, and can be used for preparing a drug combatting tumours, autoimmune or inflammatory diseases and viral infection, and in particular an anti-prostate cancer drug. Il est décrit un inhibiteur du bromodomaine figurant dans la formule II, lequel a trait au domaine des médicaments composés. Les inhibiteurs du bromodomaine 4 ont une grande valeur comme composés anti-cancéreux et anti-inflammatoires. Le composé selon l'invention a un bon effet inhibiteur sur la prolifération de cellules de cancer de la prostate, et il peut être utilisé pour la préparation d'un médicament combattant les tumeurs, les maladies auto-immunes ou inflammatoires et les infections virales, ainsi que pour la préparation d'un médicament combattant le cancer de la prostate.