[6R]-MTHF - AN EFFICIENT FOLATE ALTERNATIVE IN 5-FLUOROURACIL BASED CHEMOTHERAPY

[6R]-MTHF - AN EFFICIENT FOLATE ALTERNATIVE IN 5-FLUOROURACIL BASED CHEMOTHERAPY

The present invention relates to the treatment of solid tumors in humans such as cancer, especially colorectal cancer (CRC), which involves administering the diastereomerically pure folate adjuvant [6R]-5,10-methylenetetrahydrofolate in 5-fluorouracil (5-FU) based chemotherapy. La présente invention...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LINDBERG, PER LENNART, SUNDEN, GUNNEL ELISABETH, GUSTAVSSON, BENGT, VEDIN, ANDERS
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention relates to the treatment of solid tumors in humans such as cancer, especially colorectal cancer (CRC), which involves administering the diastereomerically pure folate adjuvant [6R]-5,10-methylenetetrahydrofolate in 5-fluorouracil (5-FU) based chemotherapy. La présente invention concerne le traitement de tumeurs solides chez des êtres humains telles que le cancer, en particulier le cancer colorectal (CRC), qui consiste à administrer l'adjuvant de folate diastéréomériquement pur [6R]-5,10-méthylènetétrahydrofolate dans une chimiothérapie à base de 5-fluorouracile (5-FU).