NEW SALT OF N-(2,6-DIETHYLPHENYL)-8-({4-[4-(DIMETHYLAMINO)PIPERIDIN-1-YL]-2-METHOXYPHENYL}AMINO)-1-METHYL-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE, ITS PREPARATION AND FORMULATIONS CONTAINING IT

NEW SALT OF N-(2,6-DIETHYLPHENYL)-8-({4-[4-(DIMETHYLAMINO)PIPERIDIN-1-YL]-2-METHOXYPHENYL}AMINO)-1-METHYL-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE, ITS PREPARATION AND FORMULATIONS CONTAINING IT

It is provided a compound consisting of N-(2,6-diethylphenyl)-8-({4-14-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl} amino)-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide phosphate of formula (II): (see formula II) and use of same in the treatment of cancer. La présente invention...

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Bibliographische Detailangaben
Hauptverfasser: CALDARELLI, MARINA, ZAMPIERI, MASSIMO, D'ARASMO, GERMANO, CANDIANI, ILARIA, D'ANELLO, MATTEO
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:It is provided a compound consisting of N-(2,6-diethylphenyl)-8-({4-14-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl} amino)-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide phosphate of formula (II): (see formula II) and use of same in the treatment of cancer. La présente invention concerne un nouveau phosphate de N-(2,6-diéthylphényl)-8-({4-[4-(diméthylamino)pipéridin-1-yl]-2-méthoxyphényl} amino)-1-méthyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide de formule (II) : (II) médicaments