ANTI-CARBAMYLATED PROTEIN ANTIBODIES AND THE RISK FOR ARTHRITIS

Antibodies against citrullinated protein antigens (ACPA) have shown their relevance for the diagnosis and possibly pathogenesis in arthritis. The present invention provides means and methods for determining antibodies against homocitrulline containing proteins or carbamylated proteins/peptides (anti...

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Hauptverfasser: SHI, JING, VAN VEELEN, PETRUS ANTONIUS, TOES, REINALDUS EVERARDUS MARIA, HUIZINGA, THOMAS WILLEM JOHANNES, TROUW, LEENDERT ADRIANUS, CERAMI, ANTHONY
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creator SHI, JING
VAN VEELEN, PETRUS ANTONIUS
TOES, REINALDUS EVERARDUS MARIA
HUIZINGA, THOMAS WILLEM JOHANNES
TROUW, LEENDERT ADRIANUS
CERAMI, ANTHONY
description Antibodies against citrullinated protein antigens (ACPA) have shown their relevance for the diagnosis and possibly pathogenesis in arthritis. The present invention provides means and methods for determining antibodies against homocitrulline containing proteins or carbamylated proteins/peptides (anti-Car P) for the classification of individuals suffering from or at risk of suffering from arthritis. Il est décrit des anticorps anti-protéines citrullinées (ACPA) qui sont pertinents pour diagnostiquer larthrite et potentiellement réaliser la pathogenèse de larthrite Linvention concerne des moyens et des méthodes pour déterminer des anticorps dirigés contre des protéines contenant de lhomocitrulline ou des protéines carbamylées/peptides carbamylés (anti-Car P) pour établir un classement des personnes souffrant darthrite ou présentant des risques de souffrir de larthrite.
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subjects INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
title ANTI-CARBAMYLATED PROTEIN ANTIBODIES AND THE RISK FOR ARTHRITIS
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