ATROPINE PHARMACEUTICAL COMPOSITIONS

The inventive subject matter is directed to compositions and methods for sterile and storage stable low-dose atropine formulations with improved stability. Most preferably, the compositions presented herein are substantially preservative free and exhibit less than 0.35% tropic acid from degradation...

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Bibliographische Detailangaben
Hauptverfasser:	PURI, NAVNEET, MOHAMMED, IRFAN A, ILITCHEV, IOURI V, AKASAPU, PREM SAGAR, ZHANG, TAO, SOPPIMATH, KUMARESH
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The inventive subject matter is directed to compositions and methods for sterile and storage stable low-dose atropine formulations with improved stability. Most preferably, the compositions presented herein are substantially preservative free and exhibit less than 0.35% tropic acid from degradation of atropine. Advantageously, contemplated formulations are also substantially free of preservatives. La présente invention concerne des compositions et des procédés pour des formulations d'atropine à faible dose stériles et stables à la conservation présentant une stabilité améliorée. De manière préférée entre toutes, les compositions de la présente invention sont sensiblement exemptes de conservateur et présentent moins de 0,35 % d'acide tropique provenant de la dégradation de l'atropine. Avantageusement, les formulations de l'invention sont également sensiblement exemptes de conservateurs.