METHOD OF DETECTING AT LEAST ONE MECHANISM OF RESISTANCE TO CARBAPENEMS BY MASS SPECTROMETRY

The invention relates to a method for the mass spectrometry-based detection of at least one marker of at least one mechanism of resistance to at least one antimicrobial agent, for at least one microorganism included in a sample. The method is characterised in that the antimicrobial agent is carbapen...

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Bibliographische Detailangaben
Hauptverfasser:	ZAMBARDI, GILLES, CHARRIER, JEAN-PHILIPPE, CHARRETIER, YANNICK, DEGOUTARMETTE, ELODIE, FRANCESCHI, CHRISTINE, CECCHINI, TIPHAINE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to a method for the mass spectrometry-based detection of at least one marker of at least one mechanism of resistance to at least one antimicrobial agent, for at least one microorganism included in a sample. The method is characterised in that the antimicrobial agent is carbapenem, and said resistance markers are proteins or peptides. Preferably, the proteins or peptides are proteins from said microorganism. Linvention concerne une méthode de détection, par spectrométrie de masse, dau moins un marqueur dau moins un mécanisme de résistance à au moins un agent antimicrobien dun microorganisme compris dans un échantillon. La méthode est caractérisée lantimicrobien, qui est un carbapénème, et les marqueurs de résistance sont des protéines ou des peptides. De préférence, lesdits protéines ou peptides sont des protéines du microorganisme.