COMPOSITIONS AND METHODS COMPRISING CO-CULTURE OF HEPATOCYTES

Provided are methods and compositions for co-culturing hepatocytes in the presence of growth- arrested stromal cells, resulting in maintenance of hepatocyte function and phenotype for an extended period of time in culture comprising at least 30 days. L'invention concerne des procédés et des com...

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Hauptverfasser:	MALAVARCA, RICHARD HAROLD, BARFIELD, SHILOH JESSE, ROACH, MARSHA LYNN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Provided are methods and compositions for co-culturing hepatocytes in the presence of growth- arrested stromal cells, resulting in maintenance of hepatocyte function and phenotype for an extended period of time in culture comprising at least 30 days. L'invention concerne des procédés et des compositions pour la co-culture d'hépatocytes en présence de cellules stromales à croissance arrêtée, conduisant au maintien de la fonction des hépatocytes et du phénotype pendant une période de temps étendue en culture comprenant au moins 30 jours.