A DRUG DELIVERY SYSTEM COMPRISING VIRUS-LIKE PARTICLES FROM JOHN CUNNINGHAM VIRUS AND METHODS PROVIDING THEREOF

The invention relates to a method for providing a drug delivery system, in particular for crossing the blood brain barrier (BBB), comprising a virus-like particle (VLP) derived from John Cunningham virus (JCV), a drug delivery system and novel VLP obtainable by said method. The method comprises step...

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Bibliographische Detailangaben
Hauptverfasser: KOSMANN, KATJA JANINA, MANNINGA, HEIKO, STAPF, MARCUS, SOTNIKOV, SERGEY, DEMINA, VICTORIA
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The invention relates to a method for providing a drug delivery system, in particular for crossing the blood brain barrier (BBB), comprising a virus-like particle (VLP) derived from John Cunningham virus (JCV), a drug delivery system and novel VLP obtainable by said method. The method comprises steps of disassembly of VLP into pentamers and reassembly into VLP.