DOSE DETERMINATION FOR IMMUNOTHERAPEUTIC AGENTS

The present invention relates to methods for determining suitable doses for administration of immunotherapeutic compounds, whose effectiveness and toxicity can vary at the same dose between individuals due to natural variations within individual subjects, such as variations in the reaction of the im...

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Hauptverfasser: JAHNDEL, VERONIKA, SAHIN, UGUR, HUSEMANN, YVES, DORER, KATHRIN, SCHWARCK-KOKARAKIS, DOREEN, ROSEMANN, ROMAN PETER, STROBL, STEFAN JOSEF CHRISTOF FRIEDRICH, JABULOWSKY, ROBERT
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention relates to methods for determining suitable doses for administration of immunotherapeutic compounds, whose effectiveness and toxicity can vary at the same dose between individuals due to natural variations within individual subjects, such as variations in the reaction of the immune system in response to administration of such immunotherapeutic compounds. L'invention concerne des procédés servant à déterminer des doses appropriées pour l'administration de composés immunothérapeutiques dont l'efficacité et la toxicité peuvent varier à la même dose entre individus en raison de variations naturelles chez ces individus, telles que des variations dans la réaction du système immunitaire en réponse à l'administration desdits composés immunothérapeutiques.