METHOD FOR PRODUCING A POLYMORPHIC FORM OF 3-[5-AMINO-4-(3-CYANOBENZOYL)-PYRAZOL-1-YL]-N-CYCLOPROPYL-4-METHYLBENZAMIDE

This invention relates to a process for the preparation of Form B of 3-[5-amino-4-(3- cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide. Also disclosed herein is Form B of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4- methylbenzamide, or pharmaceutical compositions thereof,...

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Hauptverfasser:	PEREZ, LUCIA ROMERO, SULEIMAN, OSAMA, JONES, STEWART, HARLACHER, CORNELIUS STEPHAN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention relates to a process for the preparation of Form B of 3-[5-amino-4-(3- cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide. Also disclosed herein is Form B of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4- methylbenzamide, or pharmaceutical compositions thereof, obtainable by the process described herein. L'invention concerne un procédé de préparation de la forme B de 3- [5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-méthylbenzamide. L'invention concerne également la forme B de 3- [5-amino-4-(3-cyanobenzoyle)-pyrazol-1-yl]-N-cyclopropyl-4-méthylbenzamide, ou des compositions pharmaceutiques de celui-ci, pouvant être obtenues par le procédé décrit ici.