MODIFIED CARBOHYDRATES, COMPOSITIONS COMPRISING THE SAME, AND METHODS OF MAKING AND USING THE SAME

Modified alginates are described herein along with hydrogels comprising the same. A modified alginate may be prepared by reacting alginate and an aromatic compound (e.g., an aromatic amine) and/or pH sensitive compound. The modified alginates, hydrogels, and/or methods described herein may be used t...

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Bibliographische Detailangaben
Hauptverfasser:	OPARA, EMMANUEL C, BANKS, SURYA R, WEISSENFLUH, AMBER N, WELKER, MARK E
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY COMPOSITIONS BASED THEREON DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS POLYSACCHARIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:	Modified alginates are described herein along with hydrogels comprising the same. A modified alginate may be prepared by reacting alginate and an aromatic compound (e.g., an aromatic amine) and/or pH sensitive compound. The modified alginates, hydrogels, and/or methods described herein may be used to coat and/or encapsulate at least a portion of a bioactive substance, optionally for oral delivery in humans and other animals. L'invention concerne des alginates modifiés ainsi que des hydrogels les comprenant. On peut préparer un alginate modifié en faisant réagir un alginate et un composé aromatique (par exemple une amine aromatique) et/ou un composé sensible au pH. Les alginates modifiés, les hydrogels et/ou les procédés de l'invention peuvent être utilisés pour revêtir et/ou encapsuler au moins une partie d'une substance bioactive, éventuellement pour une administration orale chez l'homme et d'autres animaux.