POLYMERASE VARIANTS AND USES THEREOF
Described herein is a variant pol6 polymerase having at least one mutation selected from H223, N224, Y225, H227,1295, Y342, T343, 1357, S360, L361,1363, S365, S366, Y367, P368, D417, E475, Y476, F478, K518, H527, T529, M531, N535, G539, P542, N545, 0546, A547, L549,1550, N552, G553, F558, A596, G603...
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| creator | MCGAW, COLIN LEDERMAN, ILYA AYER, ARUNA ARNOLD, CLEOMA SHULTZ, TYLER SCHWAB, CHARLES THAI, EILEEN |
| description | Described herein is a variant pol6 polymerase having at least one mutation selected from H223, N224, Y225, H227,1295, Y342, T343, 1357, S360, L361,1363, S365, S366, Y367, P368, D417, E475, Y476, F478, K518, H527, T529, M531, N535, G539, P542, N545, 0546, A547, L549,1550, N552, G553, F558, A596, G603, A610, V615, Y622, C623, D624,1628, Y629, R632, N635, M641, A643,1644, T647, 1648, T651,1652, K655, W656, D657, V658, H660, F662, L690 and combinations thereof.
Il est décrit une variante pol6 polymérase ayant au moins une mutation parmi les suivantes ou une combinaison de celles-ci : H223, N224, Y225, H227,1295, Y342, T343, 1357, S360, L361,1363, S365, S366, Y367, P368, D417, E475, Y476, F478, K518, H527, T529, M531, N535, G539, P542, N545, 0546, A547, L549,1550, N552, G553, F558, A596, G603, A610, V615, Y622, C623, D624,1628, Y629, R632, N635, M641, A643,1644, T647, 1648, T651,1652, K655, W656, D657, V658, H660, F662, L690. |
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Il est décrit une variante pol6 polymérase ayant au moins une mutation parmi les suivantes ou une combinaison de celles-ci : H223, N224, Y225, H227,1295, Y342, T343, 1357, S360, L361,1363, S365, S366, Y367, P368, D417, E475, Y476, F478, K518, H527, T529, M531, N535, G539, P542, N545, 0546, A547, L549,1550, N552, G553, F558, A596, G603, A610, V615, Y622, C623, D624,1628, Y629, R632, N635, M641, A643,1644, T647, 1648, T651,1652, K655, W656, D657, V658, H660, F662, L690.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; COMPOSITIONS THEREOF ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; CULTURE MEDIA ; ENZYMOLOGY ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230103&DB=EPODOC&CC=CA&NR=3028797C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230103&DB=EPODOC&CC=CA&NR=3028797C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MCGAW, COLIN</creatorcontrib><creatorcontrib>LEDERMAN, ILYA</creatorcontrib><creatorcontrib>AYER, ARUNA</creatorcontrib><creatorcontrib>ARNOLD, CLEOMA</creatorcontrib><creatorcontrib>SHULTZ, TYLER</creatorcontrib><creatorcontrib>SCHWAB, CHARLES</creatorcontrib><creatorcontrib>THAI, EILEEN</creatorcontrib><title>POLYMERASE VARIANTS AND USES THEREOF</title><description>Described herein is a variant pol6 polymerase having at least one mutation selected from H223, N224, Y225, H227,1295, Y342, T343, 1357, S360, L361,1363, S365, S366, Y367, P368, D417, E475, Y476, F478, K518, H527, T529, M531, N535, G539, P542, N545, 0546, A547, L549,1550, N552, G553, F558, A596, G603, A610, V615, Y622, C623, D624,1628, Y629, R632, N635, M641, A643,1644, T647, 1648, T651,1652, K655, W656, D657, V658, H660, F662, L690 and combinations thereof.
Il est décrit une variante pol6 polymérase ayant au moins une mutation parmi les suivantes ou une combinaison de celles-ci : H223, N224, Y225, H227,1295, Y342, T343, 1357, S360, L361,1363, S365, S366, Y367, P368, D417, E475, Y476, F478, K518, H527, T529, M531, N535, G539, P542, N545, 0546, A547, L549,1550, N552, G553, F558, A596, G603, A610, V615, Y622, C623, D624,1628, Y629, R632, N635, M641, A643,1644, T647, 1648, T651,1652, K655, W656, D657, V658, H660, F662, L690.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>COMPOSITIONS THEREOF</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFAJ8PeJ9HUNcgx2VQhzDPJ09AsJVnD0c1EIDXYNVgjxcA1y9XfjYWBNS8wpTuWF0twM8m6uIc4euqkF-fGpxQWJyal5qSXxzo7GBkYW5pbmzsaEVQAAAzIiQg</recordid><startdate>20230103</startdate><enddate>20230103</enddate><creator>MCGAW, COLIN</creator><creator>LEDERMAN, ILYA</creator><creator>AYER, ARUNA</creator><creator>ARNOLD, CLEOMA</creator><creator>SHULTZ, TYLER</creator><creator>SCHWAB, CHARLES</creator><creator>THAI, EILEEN</creator><scope>EVB</scope></search><sort><creationdate>20230103</creationdate><title>POLYMERASE VARIANTS AND USES THEREOF</title><author>MCGAW, COLIN ; LEDERMAN, ILYA ; AYER, ARUNA ; ARNOLD, CLEOMA ; SHULTZ, TYLER ; SCHWAB, CHARLES ; THAI, EILEEN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA3028797C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2023</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>COMPOSITIONS THEREOF</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>MCGAW, COLIN</creatorcontrib><creatorcontrib>LEDERMAN, ILYA</creatorcontrib><creatorcontrib>AYER, ARUNA</creatorcontrib><creatorcontrib>ARNOLD, CLEOMA</creatorcontrib><creatorcontrib>SHULTZ, TYLER</creatorcontrib><creatorcontrib>SCHWAB, CHARLES</creatorcontrib><creatorcontrib>THAI, EILEEN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MCGAW, COLIN</au><au>LEDERMAN, ILYA</au><au>AYER, ARUNA</au><au>ARNOLD, CLEOMA</au><au>SHULTZ, TYLER</au><au>SCHWAB, CHARLES</au><au>THAI, EILEEN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>POLYMERASE VARIANTS AND USES THEREOF</title><date>2023-01-03</date><risdate>2023</risdate><abstract>Described herein is a variant pol6 polymerase having at least one mutation selected from H223, N224, Y225, H227,1295, Y342, T343, 1357, S360, L361,1363, S365, S366, Y367, P368, D417, E475, Y476, F478, K518, H527, T529, M531, N535, G539, P542, N545, 0546, A547, L549,1550, N552, G553, F558, A596, G603, A610, V615, Y622, C623, D624,1628, Y629, R632, N635, M641, A643,1644, T647, 1648, T651,1652, K655, W656, D657, V658, H660, F662, L690 and combinations thereof.
Il est décrit une variante pol6 polymérase ayant au moins une mutation parmi les suivantes ou une combinaison de celles-ci : H223, N224, Y225, H227,1295, Y342, T343, 1357, S360, L361,1363, S365, S366, Y367, P368, D417, E475, Y476, F478, K518, H527, T529, M531, N535, G539, P542, N545, 0546, A547, L549,1550, N552, G553, F558, A596, G603, A610, V615, Y622, C623, D624,1628, Y629, R632, N635, M641, A643,1644, T647, 1648, T651,1652, K655, W656, D657, V658, H660, F662, L690.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | POLYMERASE VARIANTS AND USES THEREOF |
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