METHODS AND COMPOSITIONS FOR THERANOSTIC NANOPARTICLES

Disclosed are compositions and methods for identifying a solid tumor cell target. Compositions and methods for treating prostate cancer are also disclosed. Further, cancer therapeutic compositions comprising CT20p are disclosed. Nanoparticles that are conjugated with a targeting ligand that is a sub...

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Bibliographische Detailangaben
Hauptverfasser:	KHALED, ANNETTE, SANTRA, SANTIMUKUL, KAITTANIS, CHARALAMBOS, PEREZ FIGUEROA, JESUS MANUEL, GRIMM, JAN, SANTIESTEBAN, OSCAR, SESSIONS, HAMPTON
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Disclosed are compositions and methods for identifying a solid tumor cell target. Compositions and methods for treating prostate cancer are also disclosed. Further, cancer therapeutic compositions comprising CT20p are disclosed. Nanoparticles that are conjugated with a targeting ligand that is a substrate for a solid tumor-specific cell protein are disclosed. L'invention concerne des compositions et des procédés pour identifier une cible de cellule de tumeur solide. L'invention concerne par ailleurs des compositions et des procédés de traitement du cancer de la prostate. L'invention concerne en outre des compositions thérapeutiques contre le cancer comprenant le peptide CT20p. Des nanoparticules qui sont conjuguées avec un ligand de ciblage qui est un substrat pour une protéine de cellule spécifique d'une tumeur solide sont également décrites.