COMPOUNDS OF ANGIOTENSIN II RECEPTOR ANTAGONIST METABOLITE AND NEP INHIBITOR, AND PREPARATION METHODS THEREOF

Provided are a supramolecular composite comprising an angiotensin II receptor (AT1) blocking compound, a neutral endopeptidase inhibitor (NEPi), and a pharmaceutically acceptable cation. The invention further provides a method for preparing the composite and an application of the composite for prepa...

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Hauptverfasser: LI, SONG, YAN, JIE, ZHI, JIANQIONG, XU, WENJIE, ZHENG, YANXIN
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creator LI, SONG
YAN, JIE
ZHI, JIANQIONG
XU, WENJIE
ZHENG, YANXIN
description Provided are a supramolecular composite comprising an angiotensin II receptor (AT1) blocking compound, a neutral endopeptidase inhibitor (NEPi), and a pharmaceutically acceptable cation. The invention further provides a method for preparing the composite and an application of the composite for preparing a pharmaceutical product for treating heart failure. L'invention concerne un composite supramoléculaire comprenant un composé bloquant le récepteur de l'angiotensine II (AT1), un inhibiteur de l'endopeptidase neutre (NEPi) et un cation pharmaceutiquement acceptable. L'invention concerne également un procédé permettant de préparer le composite et une application du composite pour préparer un produit pharmaceutique destiné au traitement de l'insuffisance cardiaque.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title COMPOUNDS OF ANGIOTENSIN II RECEPTOR ANTAGONIST METABOLITE AND NEP INHIBITOR, AND PREPARATION METHODS THEREOF
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