COMPOUNDS OF ANGIOTENSIN II RECEPTOR ANTAGONIST METABOLITE AND NEP INHIBITOR, AND PREPARATION METHODS THEREOF

Provided are a supramolecular composite comprising an angiotensin II receptor (AT1) blocking compound, a neutral endopeptidase inhibitor (NEPi), and a pharmaceutically acceptable cation. The invention further provides a method for preparing the composite and an application of the composite for prepa...

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Bibliographische Detailangaben
Hauptverfasser:	LI, SONG, YAN, JIE, ZHI, JIANQIONG, XU, WENJIE, ZHENG, YANXIN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided are a supramolecular composite comprising an angiotensin II receptor (AT1) blocking compound, a neutral endopeptidase inhibitor (NEPi), and a pharmaceutically acceptable cation. The invention further provides a method for preparing the composite and an application of the composite for preparing a pharmaceutical product for treating heart failure. L'invention concerne un composite supramoléculaire comprenant un composé bloquant le récepteur de l'angiotensine II (AT1), un inhibiteur de l'endopeptidase neutre (NEPi) et un cation pharmaceutiquement acceptable. L'invention concerne également un procédé permettant de préparer le composite et une application du composite pour préparer un produit pharmaceutique destiné au traitement de l'insuffisance cardiaque.