PLURIPOTENT STEM CELL EXPANSION AND PASSAGE USING A STIRRED TANK BIOREACTOR
Provided herein are novel methods for expansion and passaging of cell aggregates comprising stem cells and/or differentiated cells and comprising the use of closed systems in stirred tank bioreactors. The methods of the invention permit closed system serial passage expansion of pluripotent stem cell...
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| creator | ZHANG, XIAOHUA CONWAY, KENNETH ROGER DAVIS, BRIAN MICHAEL |
| description | Provided herein are novel methods for expansion and passaging of cell aggregates comprising stem cells and/or differentiated cells and comprising the use of closed systems in stirred tank bioreactors. The methods of the invention permit closed system serial passage expansion of pluripotent stem cells and/or progeny thereof with associated pluripotency markers and differentiation potential.
L'invention concerne de nouvelles méthodes destinées à l'expansion et au repiquage d'agrégats cellulaires comprenant des cellules souches et/ou des cellules différenciées et comprenant l'utilisation de systèmes clos sur des bioréacteurs à plateforme basculante. Les méthodes de l'invention permettent une expansion du repiquage en série en système clos des cellules souches pluripotentes et/ou de leurs descendances avec des marqueurs pluripotents et un potentiel de différenciation. |
| format | Patent |
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L'invention concerne de nouvelles méthodes destinées à l'expansion et au repiquage d'agrégats cellulaires comprenant des cellules souches et/ou des cellules différenciées et comprenant l'utilisation de systèmes clos sur des bioréacteurs à plateforme basculante. Les méthodes de l'invention permettent une expansion du repiquage en série en système clos des cellules souches pluripotentes et/ou de leurs descendances avec des marqueurs pluripotents et un potentiel de différenciation.</description><language>eng ; fre</language><subject>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY ; BEER ; BIOCHEMISTRY ; CHEMISTRY ; ENZYMOLOGY ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170928&DB=EPODOC&CC=CA&NR=3014584A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170928&DB=EPODOC&CC=CA&NR=3014584A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ZHANG, XIAOHUA</creatorcontrib><creatorcontrib>CONWAY, KENNETH ROGER</creatorcontrib><creatorcontrib>DAVIS, BRIAN MICHAEL</creatorcontrib><title>PLURIPOTENT STEM CELL EXPANSION AND PASSAGE USING A STIRRED TANK BIOREACTOR</title><description>Provided herein are novel methods for expansion and passaging of cell aggregates comprising stem cells and/or differentiated cells and comprising the use of closed systems in stirred tank bioreactors. The methods of the invention permit closed system serial passage expansion of pluripotent stem cells and/or progeny thereof with associated pluripotency markers and differentiation potential.
L'invention concerne de nouvelles méthodes destinées à l'expansion et au repiquage d'agrégats cellulaires comprenant des cellules souches et/ou des cellules différenciées et comprenant l'utilisation de systèmes clos sur des bioréacteurs à plateforme basculante. Les méthodes de l'invention permettent une expansion du repiquage en série en système clos des cellules souches pluripotentes et/ou de leurs descendances avec des marqueurs pluripotents et un potentiel de différenciation.</description><subject>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY</subject><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>ENZYMOLOGY</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2017</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEKwjAQANAsDqL-w_2A0NIKrmd61tB4CZcruJUi6SRaqP-PDn6A01ve2nTR9-JiUGKFpHQFS94D3SJycoEBuYGIKWFL0CfHLeD3ORFqQJE7OLkghFaDbM1qGh9L3v3cGDiT2ss-z68hL_N4z8_8HixWRVkfjjWW1R_lA0CbLTE</recordid><startdate>20170928</startdate><enddate>20170928</enddate><creator>ZHANG, XIAOHUA</creator><creator>CONWAY, KENNETH ROGER</creator><creator>DAVIS, BRIAN MICHAEL</creator><scope>EVB</scope></search><sort><creationdate>20170928</creationdate><title>PLURIPOTENT STEM CELL EXPANSION AND PASSAGE USING A STIRRED TANK BIOREACTOR</title><author>ZHANG, XIAOHUA ; CONWAY, KENNETH ROGER ; DAVIS, BRIAN MICHAEL</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA3014584A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2017</creationdate><topic>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY</topic><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>ENZYMOLOGY</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>ZHANG, XIAOHUA</creatorcontrib><creatorcontrib>CONWAY, KENNETH ROGER</creatorcontrib><creatorcontrib>DAVIS, BRIAN MICHAEL</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ZHANG, XIAOHUA</au><au>CONWAY, KENNETH ROGER</au><au>DAVIS, BRIAN MICHAEL</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PLURIPOTENT STEM CELL EXPANSION AND PASSAGE USING A STIRRED TANK BIOREACTOR</title><date>2017-09-28</date><risdate>2017</risdate><abstract>Provided herein are novel methods for expansion and passaging of cell aggregates comprising stem cells and/or differentiated cells and comprising the use of closed systems in stirred tank bioreactors. The methods of the invention permit closed system serial passage expansion of pluripotent stem cells and/or progeny thereof with associated pluripotency markers and differentiation potential.
L'invention concerne de nouvelles méthodes destinées à l'expansion et au repiquage d'agrégats cellulaires comprenant des cellules souches et/ou des cellules différenciées et comprenant l'utilisation de systèmes clos sur des bioréacteurs à plateforme basculante. Les méthodes de l'invention permettent une expansion du repiquage en série en système clos des cellules souches pluripotentes et/ou de leurs descendances avec des marqueurs pluripotents et un potentiel de différenciation.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING SPIRITS VINEGAR WINE |
| title | PLURIPOTENT STEM CELL EXPANSION AND PASSAGE USING A STIRRED TANK BIOREACTOR |
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