A METHOD OF GENERATING A SYNTHETIC ANTIBODY LIBRARY, SAID LIBRARY AND APPLICATION(S) THEREOF
The present disclosure relates to a method of generating an antibody library, not limiting to a synthetic antibody gene expression library built on pool of consensus nucleic acid sequences by using codon replacement technology. The present disclosure also relates to a synthetic antibody library gene...
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creator | SHARMA, ANKURINA SHARMA, RASHMI HALAN, VIVEK HORA, ANURADHA NAIR, KARTHIKA TIWARI, ANURAG KUMAR DAKSHINAMURTHY, PRAVIN BHIMA RAO, SAHANA MARKANDA, NIKITHA MAITY, SUNIT UNNIKRISHNAN, DIVYA CHATTERJEE, SOHANG MALIWALAVE, AMOL IYER RODRIGUES, KAVITHA PRASAD, BHARGAV PATEL, SHIVANI KAMANAGOWDA, VEERESHA KHAN, AMIR PRAKASH CHAKRABARTY, SUBHRA GHOSH, MALOY BHATTACHARJEE, SANGHAMITRA SRINIVASAN, SANKARANARAYANAN KUMAR DUBEY, ASHVINI MUKUNDA, PAVITHRA NATARAJAN, BAIRAVABALAKUMAR KUMAR, SANTOSH RAVINDRA SHENOY, BHARATH MANJUNATH BANGALORE MUNIRAJU, YOGENDRA MURUGESAN, SATHYABALAN THANIGAIVEL, ASWINI |
description | The present disclosure relates to a method of generating an antibody library, not limiting to a synthetic antibody gene expression library built on pool of consensus nucleic acid sequences by using codon replacement technology. The present disclosure also relates to a synthetic antibody library generated by employing the method of the present disclosure and application(s) of said antibody library.
La présente invention concerne un procédé de génération d'une bibliothèque d'anticorps, ne se limitant pas à une bibliothèque d'expression génique d'anticorps synthétiques construite sur un pool de séquences d'acides nucléiques de consensus en utilisant une technologie de remplacement de codons. La présente invention concerne également une bibliothèque d'anticorps synthétiques générée par l'emploi du procédé selon la présente invention et des applications de cette bibliothèque d'anticorps. |
format | Patent |
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La présente invention concerne un procédé de génération d'une bibliothèque d'anticorps, ne se limitant pas à une bibliothèque d'expression génique d'anticorps synthétiques construite sur un pool de séquences d'acides nucléiques de consensus en utilisant une technologie de remplacement de codons. La présente invention concerne également une bibliothèque d'anticorps synthétiques générée par l'emploi du procédé selon la présente invention et des applications de cette bibliothèque d'anticorps.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMBINATORIAL CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS ; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20211019&DB=EPODOC&CC=CA&NR=3011827C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,782,887,25571,76555</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20211019&DB=EPODOC&CC=CA&NR=3011827C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SHARMA, ANKURINA</creatorcontrib><creatorcontrib>SHARMA, RASHMI</creatorcontrib><creatorcontrib>HALAN, VIVEK</creatorcontrib><creatorcontrib>HORA, ANURADHA</creatorcontrib><creatorcontrib>NAIR, KARTHIKA</creatorcontrib><creatorcontrib>TIWARI, ANURAG</creatorcontrib><creatorcontrib>KUMAR DAKSHINAMURTHY, PRAVIN</creatorcontrib><creatorcontrib>BHIMA RAO, SAHANA</creatorcontrib><creatorcontrib>MARKANDA, NIKITHA</creatorcontrib><creatorcontrib>MAITY, SUNIT</creatorcontrib><creatorcontrib>UNNIKRISHNAN, DIVYA</creatorcontrib><creatorcontrib>CHATTERJEE, SOHANG</creatorcontrib><creatorcontrib>MALIWALAVE, AMOL</creatorcontrib><creatorcontrib>IYER RODRIGUES, KAVITHA</creatorcontrib><creatorcontrib>PRASAD, BHARGAV</creatorcontrib><creatorcontrib>PATEL, SHIVANI</creatorcontrib><creatorcontrib>KAMANAGOWDA, VEERESHA</creatorcontrib><creatorcontrib>KHAN, AMIR</creatorcontrib><creatorcontrib>PRAKASH CHAKRABARTY, SUBHRA</creatorcontrib><creatorcontrib>GHOSH, MALOY</creatorcontrib><creatorcontrib>BHATTACHARJEE, SANGHAMITRA</creatorcontrib><creatorcontrib>SRINIVASAN, SANKARANARAYANAN</creatorcontrib><creatorcontrib>KUMAR DUBEY, ASHVINI</creatorcontrib><creatorcontrib>MUKUNDA, PAVITHRA</creatorcontrib><creatorcontrib>NATARAJAN, BAIRAVABALAKUMAR</creatorcontrib><creatorcontrib>KUMAR, SANTOSH</creatorcontrib><creatorcontrib>RAVINDRA SHENOY, BHARATH</creatorcontrib><creatorcontrib>MANJUNATH BANGALORE MUNIRAJU, YOGENDRA</creatorcontrib><creatorcontrib>MURUGESAN, SATHYABALAN</creatorcontrib><creatorcontrib>THANIGAIVEL, ASWINI</creatorcontrib><title>A METHOD OF GENERATING A SYNTHETIC ANTIBODY LIBRARY, SAID LIBRARY AND APPLICATION(S) THEREOF</title><description>The present disclosure relates to a method of generating an antibody library, not limiting to a synthetic antibody gene expression library built on pool of consensus nucleic acid sequences by using codon replacement technology. The present disclosure also relates to a synthetic antibody library generated by employing the method of the present disclosure and application(s) of said antibody library.
La présente invention concerne un procédé de génération d'une bibliothèque d'anticorps, ne se limitant pas à une bibliothèque d'expression génique d'anticorps synthétiques construite sur un pool de séquences d'acides nucléiques de consensus en utilisant une technologie de remplacement de codons. La présente invention concerne également une bibliothèque d'anticorps synthétiques générée par l'emploi du procédé selon la présente invention et des applications de cette bibliothèque d'anticorps.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMBINATORIAL CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS</subject><subject>LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PHYSICS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZIhxVPB1DfHwd1Hwd1Nwd_VzDXIM8fRzV3BUCI70C_FwDfF0VnD0C_F08neJVPDxdApyDIrUUQh29HSB8YDSLgqOAQE-ns5Arf5-GsGaCkCNQa7-bjwMrGmJOcWpvFCam0HezTXE2UM3tSA_PrW4IDE5NS-1JN7Z0djA0NDCyNzZmLAKAKNmMNU</recordid><startdate>20211019</startdate><enddate>20211019</enddate><creator>SHARMA, ANKURINA</creator><creator>SHARMA, RASHMI</creator><creator>HALAN, VIVEK</creator><creator>HORA, ANURADHA</creator><creator>NAIR, KARTHIKA</creator><creator>TIWARI, ANURAG</creator><creator>KUMAR DAKSHINAMURTHY, PRAVIN</creator><creator>BHIMA RAO, SAHANA</creator><creator>MARKANDA, NIKITHA</creator><creator>MAITY, SUNIT</creator><creator>UNNIKRISHNAN, DIVYA</creator><creator>CHATTERJEE, SOHANG</creator><creator>MALIWALAVE, AMOL</creator><creator>IYER RODRIGUES, KAVITHA</creator><creator>PRASAD, BHARGAV</creator><creator>PATEL, SHIVANI</creator><creator>KAMANAGOWDA, VEERESHA</creator><creator>KHAN, AMIR</creator><creator>PRAKASH CHAKRABARTY, SUBHRA</creator><creator>GHOSH, MALOY</creator><creator>BHATTACHARJEE, SANGHAMITRA</creator><creator>SRINIVASAN, SANKARANARAYANAN</creator><creator>KUMAR DUBEY, ASHVINI</creator><creator>MUKUNDA, PAVITHRA</creator><creator>NATARAJAN, BAIRAVABALAKUMAR</creator><creator>KUMAR, SANTOSH</creator><creator>RAVINDRA SHENOY, BHARATH</creator><creator>MANJUNATH BANGALORE MUNIRAJU, YOGENDRA</creator><creator>MURUGESAN, SATHYABALAN</creator><creator>THANIGAIVEL, ASWINI</creator><scope>EVB</scope></search><sort><creationdate>20211019</creationdate><title>A METHOD OF GENERATING A SYNTHETIC ANTIBODY LIBRARY, SAID LIBRARY AND APPLICATION(S) THEREOF</title><author>SHARMA, ANKURINA ; SHARMA, RASHMI ; HALAN, VIVEK ; HORA, ANURADHA ; NAIR, KARTHIKA ; TIWARI, ANURAG ; KUMAR DAKSHINAMURTHY, PRAVIN ; BHIMA RAO, SAHANA ; MARKANDA, NIKITHA ; MAITY, SUNIT ; UNNIKRISHNAN, DIVYA ; CHATTERJEE, SOHANG ; MALIWALAVE, AMOL ; IYER RODRIGUES, KAVITHA ; PRASAD, BHARGAV ; PATEL, SHIVANI ; KAMANAGOWDA, VEERESHA ; KHAN, AMIR ; PRAKASH CHAKRABARTY, SUBHRA ; GHOSH, MALOY ; BHATTACHARJEE, SANGHAMITRA ; SRINIVASAN, SANKARANARAYANAN ; KUMAR DUBEY, ASHVINI ; MUKUNDA, PAVITHRA ; NATARAJAN, BAIRAVABALAKUMAR ; KUMAR, SANTOSH ; RAVINDRA SHENOY, BHARATH ; MANJUNATH BANGALORE MUNIRAJU, YOGENDRA ; MURUGESAN, SATHYABALAN ; THANIGAIVEL, ASWINI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA3011827C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2021</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMBINATORIAL CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS</topic><topic>LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PHYSICS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>SHARMA, ANKURINA</creatorcontrib><creatorcontrib>SHARMA, RASHMI</creatorcontrib><creatorcontrib>HALAN, VIVEK</creatorcontrib><creatorcontrib>HORA, ANURADHA</creatorcontrib><creatorcontrib>NAIR, KARTHIKA</creatorcontrib><creatorcontrib>TIWARI, ANURAG</creatorcontrib><creatorcontrib>KUMAR DAKSHINAMURTHY, PRAVIN</creatorcontrib><creatorcontrib>BHIMA RAO, SAHANA</creatorcontrib><creatorcontrib>MARKANDA, NIKITHA</creatorcontrib><creatorcontrib>MAITY, SUNIT</creatorcontrib><creatorcontrib>UNNIKRISHNAN, DIVYA</creatorcontrib><creatorcontrib>CHATTERJEE, SOHANG</creatorcontrib><creatorcontrib>MALIWALAVE, AMOL</creatorcontrib><creatorcontrib>IYER RODRIGUES, KAVITHA</creatorcontrib><creatorcontrib>PRASAD, BHARGAV</creatorcontrib><creatorcontrib>PATEL, SHIVANI</creatorcontrib><creatorcontrib>KAMANAGOWDA, VEERESHA</creatorcontrib><creatorcontrib>KHAN, AMIR</creatorcontrib><creatorcontrib>PRAKASH CHAKRABARTY, SUBHRA</creatorcontrib><creatorcontrib>GHOSH, MALOY</creatorcontrib><creatorcontrib>BHATTACHARJEE, SANGHAMITRA</creatorcontrib><creatorcontrib>SRINIVASAN, SANKARANARAYANAN</creatorcontrib><creatorcontrib>KUMAR DUBEY, ASHVINI</creatorcontrib><creatorcontrib>MUKUNDA, PAVITHRA</creatorcontrib><creatorcontrib>NATARAJAN, BAIRAVABALAKUMAR</creatorcontrib><creatorcontrib>KUMAR, SANTOSH</creatorcontrib><creatorcontrib>RAVINDRA SHENOY, BHARATH</creatorcontrib><creatorcontrib>MANJUNATH BANGALORE MUNIRAJU, YOGENDRA</creatorcontrib><creatorcontrib>MURUGESAN, SATHYABALAN</creatorcontrib><creatorcontrib>THANIGAIVEL, ASWINI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SHARMA, ANKURINA</au><au>SHARMA, RASHMI</au><au>HALAN, VIVEK</au><au>HORA, ANURADHA</au><au>NAIR, KARTHIKA</au><au>TIWARI, ANURAG</au><au>KUMAR DAKSHINAMURTHY, PRAVIN</au><au>BHIMA RAO, SAHANA</au><au>MARKANDA, NIKITHA</au><au>MAITY, SUNIT</au><au>UNNIKRISHNAN, DIVYA</au><au>CHATTERJEE, SOHANG</au><au>MALIWALAVE, AMOL</au><au>IYER RODRIGUES, KAVITHA</au><au>PRASAD, BHARGAV</au><au>PATEL, SHIVANI</au><au>KAMANAGOWDA, VEERESHA</au><au>KHAN, AMIR</au><au>PRAKASH CHAKRABARTY, SUBHRA</au><au>GHOSH, MALOY</au><au>BHATTACHARJEE, SANGHAMITRA</au><au>SRINIVASAN, SANKARANARAYANAN</au><au>KUMAR DUBEY, ASHVINI</au><au>MUKUNDA, PAVITHRA</au><au>NATARAJAN, BAIRAVABALAKUMAR</au><au>KUMAR, SANTOSH</au><au>RAVINDRA SHENOY, BHARATH</au><au>MANJUNATH BANGALORE MUNIRAJU, YOGENDRA</au><au>MURUGESAN, SATHYABALAN</au><au>THANIGAIVEL, ASWINI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>A METHOD OF GENERATING A SYNTHETIC ANTIBODY LIBRARY, SAID LIBRARY AND APPLICATION(S) THEREOF</title><date>2021-10-19</date><risdate>2021</risdate><abstract>The present disclosure relates to a method of generating an antibody library, not limiting to a synthetic antibody gene expression library built on pool of consensus nucleic acid sequences by using codon replacement technology. The present disclosure also relates to a synthetic antibody library generated by employing the method of the present disclosure and application(s) of said antibody library.
La présente invention concerne un procédé de génération d'une bibliothèque d'anticorps, ne se limitant pas à une bibliothèque d'expression génique d'anticorps synthétiques construite sur un pool de séquences d'acides nucléiques de consensus en utilisant une technologie de remplacement de codons. La présente invention concerne également une bibliothèque d'anticorps synthétiques générée par l'emploi du procédé selon la présente invention et des applications de cette bibliothèque d'anticorps.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | BEER BIOCHEMISTRY CHEMISTRY COMBINATORIAL CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
title | A METHOD OF GENERATING A SYNTHETIC ANTIBODY LIBRARY, SAID LIBRARY AND APPLICATION(S) THEREOF |
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