A METHOD OF GENERATING A SYNTHETIC ANTIBODY LIBRARY, SAID LIBRARY AND APPLICATION(S) THEREOF

The present disclosure relates to a method of generating an antibody library, not limiting to a synthetic antibody gene expression library built on pool of consensus nucleic acid sequences by using codon replacement technology. The present disclosure also relates to a synthetic antibody library gene...

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Hauptverfasser: SHARMA, ANKURINA, SHARMA, RASHMI, HALAN, VIVEK, HORA, ANURADHA, NAIR, KARTHIKA, TIWARI, ANURAG, KUMAR DAKSHINAMURTHY, PRAVIN, BHIMA RAO, SAHANA, MARKANDA, NIKITHA, MAITY, SUNIT, UNNIKRISHNAN, DIVYA, CHATTERJEE, SOHANG, MALIWALAVE, AMOL, IYER RODRIGUES, KAVITHA, PRASAD, BHARGAV, PATEL, SHIVANI, KAMANAGOWDA, VEERESHA, KHAN, AMIR, PRAKASH CHAKRABARTY, SUBHRA, GHOSH, MALOY, BHATTACHARJEE, SANGHAMITRA, SRINIVASAN, SANKARANARAYANAN, KUMAR DUBEY, ASHVINI, MUKUNDA, PAVITHRA, NATARAJAN, BAIRAVABALAKUMAR, KUMAR, SANTOSH, RAVINDRA SHENOY, BHARATH, MANJUNATH BANGALORE MUNIRAJU, YOGENDRA, MURUGESAN, SATHYABALAN, THANIGAIVEL, ASWINI
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present disclosure relates to a method of generating an antibody library, not limiting to a synthetic antibody gene expression library built on pool of consensus nucleic acid sequences by using codon replacement technology. The present disclosure also relates to a synthetic antibody library generated by employing the method of the present disclosure and application(s) of said antibody library. La présente invention concerne un procédé de génération d'une bibliothèque d'anticorps, ne se limitant pas à une bibliothèque d'expression génique d'anticorps synthétiques construite sur un pool de séquences d'acides nucléiques de consensus en utilisant une technologie de remplacement de codons. La présente invention concerne également une bibliothèque d'anticorps synthétiques générée par l'emploi du procédé selon la présente invention et des applications de cette bibliothèque d'anticorps.