TETRAHYDROPYRANYL AMINO-PYRROLOPYRIMIDINONE AND METHODS OF USE THEREOF

TETRAHYDROPYRANYL AMINO-PYRROLOPYRIMIDINONE AND METHODS OF USE THEREOF

The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt thereof, tautomer, prodrug, solvate, metabolite, polymorph, analog or derivative thereof, which modulates the activity of BTK, a pharmaceutical composition comprising the compound of Formula (I), and a method...

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Bibliographische Detailangaben
Hauptverfasser: TSUNEMI, TOMOYUKI, NAKAYAMA, KIYOSHI, INAGAKI, HIROAKI, LAPIERRE, JEAN-MARC, EATHIRAJ, SUDHARSHAN, OTA, YUSUKE, SCHWARTZ, BRIAN, MOMOSE, TAKAYUKI, NAMDEV, NIVEDITA
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The application relates to a compound of Formula (I): or a pharmaceutically acceptable salt thereof, tautomer, prodrug, solvate, metabolite, polymorph, analog or derivative thereof, which modulates the activity of BTK, a pharmaceutical composition comprising the compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role. L'invention concerne un composé de Formule (I) : ou un sel pharmaceutiquement acceptable de celui-ci, un tautomère, un promédicament, un solvate, un métabolite, un polymorphe, un analogue ou un dérivé de ceux-ci, qui module l'activité de la BTK, une composition pharmaceutique comprenant le composé de Formule (I) et un procédé de traitement ou de prévention d'une maladie dans laquelle la BTK joue un rôle.