2-PHENYL-3-(PIPERAZINOMETHYL)IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS BLOCKERS OF TASK-1 AND TASK-2 CHANNELS, FOR THE TREATMENT OF SLEEP-RELATED BREATHING DISORDERS

2-PHENYL-3-(PIPERAZINOMETHYL)IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS BLOCKERS OF TASK-1 AND TASK-2 CHANNELS, FOR THE TREATMENT OF SLEEP-RELATED BREATHING DISORDERS

The present application relates to compounds of the formula (I) (see formula I) and the salts, solvates and solvates of the salts thereof, to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases, and to their use for preparing medicam...

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Bibliographische Detailangaben
Hauptverfasser: ALBUS, UDO, ROSENSTEIN, BJORN, MEIER, HEINRICH, DELBECK, MARTINA, GEHRING, DORIS, MOSIG, JOHANNA, MULLER, THOMAS, LUSTIG, KLEMENS, TOSCHI, LUISELLA, HAHN, MICHAEL
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:The present application relates to compounds of the formula (I) (see formula I) and the salts, solvates and solvates of the salts thereof, to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases, and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for treatment and/or prevention of respiratory disorders including, sleep-related respiratory disorders such as obstructive sleep apnoeas and central sleep apnoeas and snoring. Il est décrit des composés de formule (I) et des sels, des solvates et des solvates de leurs sels, des procédés pour leur production, leur utilisation seule ou en combinaison dans le traitement et/ou la prévention de maladies et leur utilisation dans la production de médicaments destinés au traitement et/ou la prévention de maladies, notamment le traitement et/ou à la prévention de troubles respiratoires, y compris les troubles respiratoires liés au sommeil comme l'apnée obstructive du sommeil et l'apnée centrale du sommeil, et le ronflement.