BENZOPYRAN DERIVATIVES AND USES THEREOF
This document relates to the use of a compound to treat one or more of psoriasis, hemophagocytic lymphohistiocytosis, Alzheimer's disease, excessive inflammation due to cytokine release, respiratory diseases, or neuronal inflammation, in which the compound has the stTucture of formula I: and wh...
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| creator | KASTELIC, TANIA CHENEVAL, DOMINIQUE |
| description | This document relates to the use of a compound to treat one or more of psoriasis, hemophagocytic lymphohistiocytosis, Alzheimer's disease, excessive inflammation due to cytokine release, respiratory diseases, or neuronal inflammation, in which the compound has the stTucture of formula I: and wherein: each of RI, R2, R3, R4, and R5 are, independently from each other, H, OH, NO2, COOCH3, COOH, halogen, (Ci-C4) alkyl, (Ci-C4) alkenyl, (Ci-C4) alkoxy, (Ci-C4) alkyl-C00-, OCOCH3, 0(Ci-C4) alkyl, 0(Ci-C4) alkenyl, 0(C2-C4) alkoxy, 0(Ci-C4) alkyl-COO-, CN, alkyl-CONH, 0-alkyl-CONH, or an organic group; wherein, Y is: each of R6, R7, R9, and R10 are, independently from each other, H, OH, NO2, COOCH3, COOH, halogen, (Ci-C4) alkyl, (Ci-C4) alkenyl, (Ci-C4) alkoxy, (Ci-C4) alkyl-COO-, OCOCH3, 0(Ci-C4) alkyl, 0(Ci-C4) alkenyl, 0(C2-C4) alkoxy, 0(Ci-C4) alkyl-COO-, CN, or an organic group; and R8 is COOCH3.
La présente invention concerne des composés utiles pour le traitement ou la prévention de troubles présentant une étiologie associée à une libération excessive de cytokines ou de chimiokines, ou comprenant celle-ci. Lesdits composés sont également utiles pour le traitement du cancer, de troubles inflammatoires et de troubles associés à une stabilité ou traduction accrue d'ARNm qui comprend une séquence d'instabilité de l'ARNm. |
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La présente invention concerne des composés utiles pour le traitement ou la prévention de troubles présentant une étiologie associée à une libération excessive de cytokines ou de chimiokines, ou comprenant celle-ci. Lesdits composés sont également utiles pour le traitement du cancer, de troubles inflammatoires et de troubles associés à une stabilité ou traduction accrue d'ARNm qui comprend une séquence d'instabilité de l'ARNm.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240213&DB=EPODOC&CC=CA&NR=2996064C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240213&DB=EPODOC&CC=CA&NR=2996064C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KASTELIC, TANIA</creatorcontrib><creatorcontrib>CHENEVAL, DOMINIQUE</creatorcontrib><title>BENZOPYRAN DERIVATIVES AND USES THEREOF</title><description>This document relates to the use of a compound to treat one or more of psoriasis, hemophagocytic lymphohistiocytosis, Alzheimer's disease, excessive inflammation due to cytokine release, respiratory diseases, or neuronal inflammation, in which the compound has the stTucture of formula I: and wherein: each of RI, R2, R3, R4, and R5 are, independently from each other, H, OH, NO2, COOCH3, COOH, halogen, (Ci-C4) alkyl, (Ci-C4) alkenyl, (Ci-C4) alkoxy, (Ci-C4) alkyl-C00-, OCOCH3, 0(Ci-C4) alkyl, 0(Ci-C4) alkenyl, 0(C2-C4) alkoxy, 0(Ci-C4) alkyl-COO-, CN, alkyl-CONH, 0-alkyl-CONH, or an organic group; wherein, Y is: each of R6, R7, R9, and R10 are, independently from each other, H, OH, NO2, COOCH3, COOH, halogen, (Ci-C4) alkyl, (Ci-C4) alkenyl, (Ci-C4) alkoxy, (Ci-C4) alkyl-COO-, OCOCH3, 0(Ci-C4) alkyl, 0(Ci-C4) alkenyl, 0(C2-C4) alkoxy, 0(Ci-C4) alkyl-COO-, CN, or an organic group; and R8 is COOCH3.
La présente invention concerne des composés utiles pour le traitement ou la prévention de troubles présentant une étiologie associée à une libération excessive de cytokines ou de chimiokines, ou comprenant celle-ci. Lesdits composés sont également utiles pour le traitement du cancer, de troubles inflammatoires et de troubles associés à une stabilité ou traduction accrue d'ARNm qui comprend une séquence d'instabilité de l'ARNm.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFB3cvWL8g-IDHL0U3BxDfIMcwzxDHMNVnD0c1EIDQYyQjxcg1z93XgYWNMSc4pTeaE0N4O8m2uIs4duakF-fGpxQWJyal5qSbyzo5GlpZmBmYmzMWEVAHHWIyo</recordid><startdate>20240213</startdate><enddate>20240213</enddate><creator>KASTELIC, TANIA</creator><creator>CHENEVAL, DOMINIQUE</creator><scope>EVB</scope></search><sort><creationdate>20240213</creationdate><title>BENZOPYRAN DERIVATIVES AND USES THEREOF</title><author>KASTELIC, TANIA ; CHENEVAL, DOMINIQUE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2996064C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>KASTELIC, TANIA</creatorcontrib><creatorcontrib>CHENEVAL, DOMINIQUE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KASTELIC, TANIA</au><au>CHENEVAL, DOMINIQUE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>BENZOPYRAN DERIVATIVES AND USES THEREOF</title><date>2024-02-13</date><risdate>2024</risdate><abstract>This document relates to the use of a compound to treat one or more of psoriasis, hemophagocytic lymphohistiocytosis, Alzheimer's disease, excessive inflammation due to cytokine release, respiratory diseases, or neuronal inflammation, in which the compound has the stTucture of formula I: and wherein: each of RI, R2, R3, R4, and R5 are, independently from each other, H, OH, NO2, COOCH3, COOH, halogen, (Ci-C4) alkyl, (Ci-C4) alkenyl, (Ci-C4) alkoxy, (Ci-C4) alkyl-C00-, OCOCH3, 0(Ci-C4) alkyl, 0(Ci-C4) alkenyl, 0(C2-C4) alkoxy, 0(Ci-C4) alkyl-COO-, CN, alkyl-CONH, 0-alkyl-CONH, or an organic group; wherein, Y is: each of R6, R7, R9, and R10 are, independently from each other, H, OH, NO2, COOCH3, COOH, halogen, (Ci-C4) alkyl, (Ci-C4) alkenyl, (Ci-C4) alkoxy, (Ci-C4) alkyl-COO-, OCOCH3, 0(Ci-C4) alkyl, 0(Ci-C4) alkenyl, 0(C2-C4) alkoxy, 0(Ci-C4) alkyl-COO-, CN, or an organic group; and R8 is COOCH3.
La présente invention concerne des composés utiles pour le traitement ou la prévention de troubles présentant une étiologie associée à une libération excessive de cytokines ou de chimiokines, ou comprenant celle-ci. Lesdits composés sont également utiles pour le traitement du cancer, de troubles inflammatoires et de troubles associés à une stabilité ou traduction accrue d'ARNm qui comprend une séquence d'instabilité de l'ARNm.</abstract><oa>free_for_read</oa></addata></record> |
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| title | BENZOPYRAN DERIVATIVES AND USES THEREOF |
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