PROBES FOR IMAGING HUNTINGTIN PROTEIN

The invention pertains to imaging agents comprising a compound of Formula I, and the use of such imaging agents labeled with positron-emitting radionuclides to generate an image to detect the presence or absence of mutant huntingtin protein (mHTT protein) or aggregates thereof in an individual. L�...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	MILLS, MATTHEW ROBERT, JOHNSON, PETER DAVID, PRIME, MICHAEL EDWARD, BARD, JONATHAN, KRULLE, THOMAS MARTIN, MARSTON, RICHARD WALDRON, WITYAK, JOHN, CLARK-FREW, DANIEL, HAYES, SARAH, GREEN, SAMANTHA LOUISE JONES, DOMINGUEZ, CELIA, HIGGINS, DUANE, COE, SAMUEL, BROWN, CHRISTOPHER JOHN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The invention pertains to imaging agents comprising a compound of Formula I, and the use of such imaging agents labeled with positron-emitting radionuclides to generate an image to detect the presence or absence of mutant huntingtin protein (mHTT protein) or aggregates thereof in an individual. L'invention concerne des agents d'imagerie comprenant un composé de formule (I) ou un sel pharmaceutiquement acceptable de celui-ci, et leurs procédés d'utilisation. (I).