PYRROLIDINYL AND PIPERIDINYL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF USEFUL AS GLS1 INHIBITORS

Disclosed herein are compounds and compositions useful in the treatment of GLSl mediated diseases, such as cancer, having the structure of Formula (I). Methods of inhibition GLSl activity in a human or animal subject are also provided. L'invention concerne des composés et des compositions utile...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	BURKE, JASON P, HAN, MICHELLE, PETROCCHI, ALESSIA, LEWIS, RICHARD THOMAS, REYNA, NAPHTALI, HAMILTON, MATTHEW, SOTH, MICHAEL J, JONES, PHILIP, HEFFERNAN, TIMOTHY
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Disclosed herein are compounds and compositions useful in the treatment of GLSl mediated diseases, such as cancer, having the structure of Formula (I). Methods of inhibition GLSl activity in a human or animal subject are also provided. L'invention concerne des composés et des compositions utiles dans le traitement de maladies médiées par la GLSI, telles que le cancer, possédant la structure de formule (I). L'invention concerne également des méthodes d'inhibition de l'activité de GLS1 chez un sujet humain ou animal.