FUSION PEPTIDES COMPRISING DISINTEGRIN BINDING TO INTEGRIN .ALPHA.V.BETA.X OR .ALPHA.5.BETA.1 AND THEIR USE IN TREATING AN ANGIOGENIC DISEASE

The present invention relates to a biologic that inhibits angiogenesis. In particular, the present invention relates to fusion proteins that inhibit the integrin activated pathway and one other angiogenic factor-activated pathway, the compositions of these fusion proteins, as well as methods for pro...

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Bibliographische Detailangaben
Hauptverfasser:	WU, PEI-TZU, CHERUKURY, MADHU, SHIU, JIA-HAU, ZEN, KEVIN, NGUYEN, TAN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to a biologic that inhibits angiogenesis. In particular, the present invention relates to fusion proteins that inhibit the integrin activated pathway and one other angiogenic factor-activated pathway, the compositions of these fusion proteins, as well as methods for producing and using the same. La présente invention concerne un agent biologique qui inhibe l'angiogenèse. En particulier, l'invention porte sur des protéines de fusion qui inhibent la voie activée par l'intégrine et une autre voie activée par un facteur angiogénique, sur les compositions de ces protéines de fusion, ainsi que sur leurs procédés de production et d'utilisation.