ACYLATED 4-AMINOPIPERIDINES AS INHIBITORS OF SERINE PALMITOYLTRANSFERASE
The present invention relates to a compound of the following general formula: (see formula I) or a salt thereof, which may be useful for the treatment or prevention of SPT-related diseases including cancer and congenital diseases associated with sphingolipid accumulation including Niemann-Pick disea...
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| creator | IMAMURA, SHINICHI ASANO, YASUTOMI SANO, OSAMU KURASAWA, OSAMU HIRATA, YASUHIRO TANAKA, YUTA KITAMURA, SHUJI KOJIMA, TAKUTO IWAMURA, NAOKI YONEMORI, KAZUKO MIYAMOTO, YASUFUMI ARAI, RYOSUKE WONG, TZU-TSHIN SAITO, BUNNAI |
| description | The present invention relates to a compound of the following general formula: (see formula I) or a salt thereof, which may be useful for the treatment or prevention of SPT-related diseases including cancer and congenital diseases associated with sphingolipid accumulation including Niemann-Pick disease.
Il est décrit un composé qui peut être utile aux fins de traitement ou de prévention de maladies liées à la sérine palmitoyltransférase, y compris le cancer et les maladies congénitales associées à l'accumulation de sphingolipides (y compris la maladie de Niemann-Pick). |
| format | Patent |
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Il est décrit un composé qui peut être utile aux fins de traitement ou de prévention de maladies liées à la sérine palmitoyltransférase, y compris le cancer et les maladies congénitales associées à l'accumulation de sphingolipides (y compris la maladie de Niemann-Pick).</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | ACYLATED 4-AMINOPIPERIDINES AS INHIBITORS OF SERINE PALMITOYLTRANSFERASE |
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