ACYLATED 4-AMINOPIPERIDINES AS INHIBITORS OF SERINE PALMITOYLTRANSFERASE

The present invention relates to a compound of the following general formula: (see formula I) or a salt thereof, which may be useful for the treatment or prevention of SPT-related diseases including cancer and congenital diseases associated with sphingolipid accumulation including Niemann-Pick disea...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	IMAMURA, SHINICHI, ASANO, YASUTOMI, SANO, OSAMU, KURASAWA, OSAMU, HIRATA, YASUHIRO, TANAKA, YUTA, KITAMURA, SHUJI, KOJIMA, TAKUTO, IWAMURA, NAOKI, YONEMORI, KAZUKO, MIYAMOTO, YASUFUMI, ARAI, RYOSUKE, WONG, TZU-TSHIN, SAITO, BUNNAI
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to a compound of the following general formula: (see formula I) or a salt thereof, which may be useful for the treatment or prevention of SPT-related diseases including cancer and congenital diseases associated with sphingolipid accumulation including Niemann-Pick disease. Il est décrit un composé qui peut être utile aux fins de traitement ou de prévention de maladies liées à la sérine palmitoyltransférase, y compris le cancer et les maladies congénitales associées à l'accumulation de sphingolipides (y compris la maladie de Niemann-Pick).