PHARMACEUTICAL FORMULATIONS OF A BRUTON'S TYROSINE KINASE INHIBITOR
Described herein are pharmaceutical formulations of Bruton's tyrosine kinase (Btk) inhibitor 1- ((R)-3-(4-amino-3-(4-phenoxyphenyl)-lH-pyrazolo[3,4-d]pyrimidin-l-yl)piperidin-l-yl)prop-2- en-l-one. Also disclosed are methods of using the Btk inhibitor, alone or in combination with other therape...
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Zusammenfassung: | Described herein are pharmaceutical formulations of Bruton's tyrosine kinase (Btk) inhibitor 1- ((R)-3-(4-amino-3-(4-phenoxyphenyl)-lH-pyrazolo[3,4-d]pyrimidin-l-yl)piperidin-l-yl)prop-2- en-l-one. Also disclosed are methods of using the Btk inhibitor, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.
L'invention concerne des formulations pharmaceutiques d'un inhibiteur de la tyrosine kinase de Bruton (Btk), le 1-((R)-3-(4-amino-3-(4-phénoxyphényl)-1H-pyrazolo [3,4-d] pyrimidin-1-yl) pipéridin-1-yl) prop-2-én-1-one. L'invention concerne des procédés d'utilisation de l'inhibiteur de Btk, seul ou en combinaison avec d'autres agents thérapeutiques, pour le traitement de maladies ou de pathologies auto-immunes, de maladies ou de pathologies hétéro-immunes, du cancer, y compris du lymphome, et de maladies ou de pathologies inflammatoires. |
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