SUBSTITUTED 9-DEAZAADENINE DERIVATES AND PHARMACEUTICAL COMPOSTITIONS THEREOF USEFUL IN THE TREATMENT OF H.PYLORI INFECTION

Methods of treating infections due to Helicobacter pylori (H. pylori), in particular in subjects haying a peptic ulcer, are disclosed where the methods comprise administering inhibitors of H. pylori MTAN (5'-methylthioadenosine nucleosidase) to the subject, where the inhibitor has the formula L...

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Bibliographische Detailangaben
Hauptverfasser: SCHRAMM, VERN L, GULAB, SHIVALI ASHWIN, CLINCH, KEITH
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Methods of treating infections due to Helicobacter pylori (H. pylori), in particular in subjects haying a peptic ulcer, are disclosed where the methods comprise administering inhibitors of H. pylori MTAN (5'-methylthioadenosine nucleosidase) to the subject, where the inhibitor has the formula La présente invention concerne des méthodes de traitement d'infections dues à Helicobacter pylori (H. pylori), en particulier chez des sujets atteints d'un ulcère gastro-duodénal, lesdites méthodes consistant à administrer au sujet des inhibiteurs de la MTAN (5'-méthylthioadénosine nucléosidase) de H. pylori.