HYDROXY CONTAINING FXR (NR1H4) MODULATING COMPOUNDS
The present invention relates to compounds (1) which bind to the NR1 H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the compounds (1) for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear recepto...
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Zusammenfassung: | The present invention relates to compounds (1) which bind to the NR1 H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the compounds (1) for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.
La présente invention concerne des composés qui se lient au récepteur NR1 H4 (FXR) et qui agissent comme agonistes de FXR. L'invention concerne en outre l'utilisation de ces composés (1) pour la préparation d'un médicament destiné au traitement de maladies et/ou d'états pathologiques par liaison dudit récepteur nucléaire auxdits composés, ainsi qu'un procédé de synthèse desdits composés. |
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