HIGH EFFICIENCY, SMALL VOLUME NUCLEIC ACID SYNTHESIS

The disclosure generally relates to compositions and methods for the production of nucleic acid molecules. In some aspects, the invention allows for the microscale generation of nucleic acid molecules, optionally followed by assembly of these nucleic acid molecules into larger molecules. In some asp...

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Bibliographische Detailangaben
Hauptverfasser:	LIANG, XIQUAN, NOTKA, FRANK, POEHMERER, THOMAS, ZEIDLER, ANDREAS, KUHN, PHILLIP, HEIL, KORBINIAN, TREFZER, AXEL, KATZEN, FEDERICO, FONNUM, GEIR, ANDERSSON, KRISTIAN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLIDMATERIALS OR FLUIDS MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROMSOLID MATERIALS OR FLUIDS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATICTABLES OR JIGS SPIRITS SUGARS TRANSPORTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The disclosure generally relates to compositions and methods for the production of nucleic acid molecules. In some aspects, the invention allows for the microscale generation of nucleic acid molecules, optionally followed by assembly of these nucleic acid molecules into larger molecules. In some aspects, the invention allows for efficient production of nucleic acid molecules (e.g., large nucleic acid molecules such as genomes). La présente invention concerne de façon générale des compositions et des méthodes de production de molécules d'acides nucléiques. L'invention permet, selon certains aspects, la génération à micro-échelle de molécules d'acides nucléiques, éventuellement suivie par l'assemblage de ces molécules d'acides nucléiques en molécules de plus grande taille. L'invention permet, selon d'autres aspects, la production efficace de molécules d'acides nucléiques (par exemple, de molécules d'acides nucléiques de grande taille telles que des génomes).