MODULATORS OF CA2+ RELEASE-ACTIVATED CA2+ (CRAC) CHANNELS AND PHARMACEUTICAL USES THEREOF

Described herein are compounds that modulate the activity of CRAC channels, methods of making such compounds, pharmaceutical compositions, and medicaments containing such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with CRAC channe...

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Bibliographische Detailangaben
Hauptverfasser: GREENBERG, MILTON L, MUZAFFERY, OMED S, RANSOM, JOHN T, NEWMAN, ANDREW C, WHITE, CLAYTON A
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Described herein are compounds that modulate the activity of CRAC channels, methods of making such compounds, pharmaceutical compositions, and medicaments containing such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with CRAC channel activity. L'invention concerne des composés qui modulent l'activité de canaux CRAC, des procédés de préparation de tels composés, des compositions pharmaceutiques et des médicaments contenant de tels composés, ainsi que des méthodes d'utilisation de tels composés pour traiter des états, des pathologies ou des troubles associés à l'activité des canaux CRAC.