SUBSTITUTED 2,4 DIAMINO-QUINOLINE AS NEW ANTICANCER AGENTS

The present invention relates to novel 2-primary amino-4-secondary amino-quinoline derivatives of formula I: (see formula I) their manufacture, pharmaceutical compositions comprising them and their use as medicaments. The active compounds of the present invention are useful for the treatment and pre...

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Bibliographische Detailangaben
Hauptverfasser:	DUBRAY, CLARISSE, BRUN, SONIA, NICOLAS, GREGORY, HALFON, PHILIPPE, BASSISSI, FIRAS, BERET, ANTOINE, COURCAMBECK, JEROME
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to novel 2-primary amino-4-secondary amino-quinoline derivatives of formula I: (see formula I) their manufacture, pharmaceutical compositions comprising them and their use as medicaments. The active compounds of the present invention are useful for the treatment and prevention of proliferative neoplastic and non-neoplastic diseases. La présente invention concerne de nouveaux dérivés de 2-amino primaire-4-amino secondaire-quinoléine, leur fabrication, des compositions pharmaceutiques les comprenant et leur utilisation en tant que médicaments. Les composés actifs de la présente invention sont utiles pour le traitement et la prévention de maladies prolifératives néoplasiques et non néoplasiques.