IRE-1.ALPHA. INHIBITORS

Compounds which directly inhibit IRE-la activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response and can be used as single agents or in combination therapies.

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Bibliographische Detailangaben
Hauptverfasser:	ZENG, QUINGPING, LONERGAN, DAVID GREGORY, PALLAI, PETER V, PATTERSON, JOHN BRUCE, FLYNN, GARY A
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Compounds which directly inhibit IRE-la activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response and can be used as single agents or in combination therapies.