PIPERIDINE SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES WITH INHIBITORY ACTIVITY ON THE REPLICATION OF THE RESPIRATORY SYNCYTIAL VIRUS (RSV)

The invention concerns novel substituted bicyclic pyrazolo pyrimidine compounds of formula (I) having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention further concerns the preparation of such novel compounds,...

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Bibliographische Detailangaben
Hauptverfasser:	HU, LILI, DEMIN, SAMUEL DOMINIQUE, RABOISSON, PIERRE JEAN-MARIE BERNARD, JONCKERS, TIM HUGO MARIA, COOYMANS, LUDWIG PAUL, TAHRI, ABDELLAH, VENDEVILLE, SANDRINE MARIE HELENE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention concerns novel substituted bicyclic pyrazolo pyrimidine compounds of formula (I) having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention further concerns the preparation of such novel compounds, compositions comprising these compounds, and the compounds for use in the treatment of respiratory syncytial virus infection. La présente invention concerne de nouveaux composés bicycliques substitués de pyrazolo-pyrimidine de formule (I), ayant une activité antivirale, en particulier une activité inhibitrice sur la réplication du virus respiratoire syncytial (VRS). L'invention concerne en outre la préparation de tels nouveaux composés, des compositions contenant ces composés, et les composés destinés à être utilisés dans le traitement d'une infection due au virus respiratoire syncytial.