SPIROCYCLIC INHIBITORS OF CATHEPSIN C

This invention relates to a compound of formula (I) wherein A and Cy have one of the meanings as indicated in the specification and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same and methods of using the same as agents for treatment and/or prevention of disea...

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Bibliographische Detailangaben
Hauptverfasser:	GRAUERT, MATTHIAS, VINTONYAK, VIKTOR, GRUNDL, MARC, PAUTSCH, ALEXANDER
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention relates to a compound of formula (I) wherein A and Cy have one of the meanings as indicated in the specification and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases. La présente invention concerne un composé de formule (I) dans laquelle A et Cy présentent l'une des significations tel qu'indiqué dans la description et leur utilisation comme inhibiteurs de la Cathepsine C, des compositions pharmaceutiques le contenant et ses procédés d'utilisation en tant qu'agents de traitement et/ou de prévention de maladies associées à l'activité de la dipeptidyl peptidase I, par exemple les maladies respiratoires.