7-(MORPHOLINYL)-2-(N-PIPERAZINYL) METHYL THIENO [2, 3-C] PYRIDINE DERIVATIVES AS ANTICANCER DRUGS

7-(MORPHOLINYL)-2-(N-PIPERAZINYL) METHYL THIENO [2, 3-C] PYRIDINE DERIVATIVES AS ANTICANCER DRUGS

The present application relates to a series of substituted 7-(morpholinyl)-2-(N-pi perazi n yl )-m ethyl thi en o [2, 3 -c] pyri din es of form ul a I, and to i n term edi ates of form ul a III: Pharmaceutical compositions comprising the compounds of Formula I are also included. The compounds of for...

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Hauptverfasser: NANNAPANENI, VENKAIAH CHOWDARY, MUDDASANI, PULLA REDDY, PILLI, RAMA KRISHNA, RAVI, JANAKI RAMA RAO, THOOTA, SANDEEP KUMAR, ADIBHATLA, KALI SATYA BHUJANGA RAO, MADDULA, LAKSHMANA VISWA VENKATA PAVAN KUMAR, VUPPALAPATI, NAGA VASANTA SRINIVASU, KONAKANCHI, DURGA PRASAD, PULA, SUBBA RAO, KONDURI, SRINIVASA KRISHNA MURTHY
Format: Patent
Sprache:eng ; fre
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:The present application relates to a series of substituted 7-(morpholinyl)-2-(N-pi perazi n yl )-m ethyl thi en o [2, 3 -c] pyri din es of form ul a I, and to i n term edi ates of form ul a III: Pharmaceutical compositions comprising the compounds of Formula I are also included. The compounds of formula I and the pharmaceutical compositions thereof may be for use in the treatment of the human or animal body, such as for the treatment of cancers including, for example, lung cancer, pancreatic cancer, prostate cancer, breast cancer, brain cancer or ovarian cancer. La présente invention concerne une nouvelle série de dérivés de 7-(morpholinyl)-2-(N-pipérazinyle)-méthylthiéno[2, 3-c]pyridines substitués représentés par la formule I dans Laquelle R1, R2, R3 et R4 sont tels que définis dans la description.