COMPOUND HAVING GPR119 AGONISTIC ACTIVITY, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION INCLUDING THE SAME AS EFFECTIVE COMPONENT

The present invention relates to a novel compound having a GPR1 19 agonistic activity having [Chemical Formula 1] (see formula 1) an isomer or a pharmaceutically acceptable salt thereof, a method for preparing the same, and a pharmaceutical composition including the same as an effective component. T...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	YANG, EUN KYOUNG, KIM, YOON JUNG, LEE, JAE YOUNG, SHIN, CHANG YELL, CHAE, YU NA, KIM, TAE HYOUNG, JUNG, IL HOON, KIM, MI KYUNG, BAEK, GYE RIM, SON, MOON HO, AHN, CHI YOUNG, YANG, JAE SUNG, CHEONG, YE HWANG, LEE, HYO JU, KANG, SO MI
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to a novel compound having a GPR1 19 agonistic activity having [Chemical Formula 1] (see formula 1) an isomer or a pharmaceutically acceptable salt thereof, a method for preparing the same, and a pharmaceutical composition including the same as an effective component. The present invention has an effective hypoglycemic action and an effect on pancreatic beta cells, and also improves lipid metabolism which is a chronic cardiovascular risk factor, thereby having a treatment and/or prevention effect of a metabolic disease such as diabetes. La présente invention concerne un nouveau composé ayant une activité agoniste GPR1 19, un procédé pour le préparer, et une composition pharmaceutique le comprenant comme constituant efficace. La présente invention présente une action hypoglycémiante efficace et un effet sur les cellules pancréatiques bêta, et améliore également le métabolisme des lipides qui est un facteur de risque cardiovasculaire chronique, ayant de là un effet de traitement et/ou de prévention d'une maladie métabolique telle que le diabète.