CRYSTALLINE FORM OF NICOTINAMIDE RIBOSIDE

Provided are crystalline forms of nicotinamide riboside, including a Form I of nicotinamide riboside chloride according to formula (I). Also disclosed are pharmaceutical compositions comprising the crystalline Form I of nicotinamide riboside chloride, and methods of producing such pharmaceutical com...

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Bibliographische Detailangaben
Hauptverfasser:	MORRILL, WESTIN M, STANDEN, MICHAEL C, CARLSON, ERIK C
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SUGARS
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Beschreibung
Zusammenfassung:	Provided are crystalline forms of nicotinamide riboside, including a Form I of nicotinamide riboside chloride according to formula (I). Also disclosed are pharmaceutical compositions comprising the crystalline Form I of nicotinamide riboside chloride, and methods of producing such pharmaceutical compositions. In other aspects, the present disclosure pertains to methods comprising administering to a subject the crystalline Form I of nicotinamide riboside chloride. The present disclosure also provides methods of preparing the crystalline Form I of nicotinamide riboside chloride. Also provided are a crystalline Form I of nicotinamide riboside chloride that is prepared according to any of the disclosed methods for preparing the crystalline Form I. La présente invention concerne des formes cristallines du riboside de nicotinamide, comprenant une forme I de chlorure de riboside de nicotinamide selon la formule (I). L'invention concerne également des compositions pharmaceutiques, comprenant la forme cristalline I du chlorure de riboside de nicotinamide, et des procédés de production de telles compositions pharmaceutiques. Selon d'autres aspects, la présente invention se rapporte à des procédés impliquant l'administration à un sujet de la forme cristalline I du chlorure de riboside de nicotinamide. La présente invention concerne également des procédés de préparation de la forme cristalline I du chlorure de riboside de nicotinamide. L'invention concerne encore une forme cristalline I du chlorure de riboside de nicotinamide qui est préparée selon l'un quelconque des procédés de préparation de la forme cristalline I selon l'invention.