CARBOHYDRATE ESTER ADJUVANTS

The present invention relates to a family of carbohydrate monosulphate fatty acid esters, which contain less than 10 mole % of carbohydrate polysulphate fatty acid esters, and to a method of preparation thereof. The monosulphate carbohydrate esters according to the invention comprise one sulphate es...

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Bibliographische Detailangaben
Hauptverfasser:	PLATENBURG, PETER PAUL L. I, VAN DEN BOSCH, JOHANNES F, HILGERS, LUCAS A. TH
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	The present invention relates to a family of carbohydrate monosulphate fatty acid esters, which contain less than 10 mole % of carbohydrate polysulphate fatty acid esters, and to a method of preparation thereof. The monosulphate carbohydrate esters according to the invention comprise one sulphate ester and at least one fatty acid and are among others useful as adjuvants for immunological products such as vaccines. La présente invention concerne une famille d'esters d'acide gras de monosulfate glucidique, qui contiennent moins de 10 % en moles d'esters d'acide gras de polysulfate glucidique et un procédé pour les préparer. Les esters glucidiques de monosulfate selon l'invention comprennent un ester de sulfate et au moins un acide gras et sont, entre autres, utiles en tant qu'adjuvants pour des produits immunologiques comme des vaccins.